CeraVe Anti-Itch Pramoxine Lotion for Bedside Self Care Routine, Fragrance Free Hydration for Sensitive Skin 8 oz
CeraVe Anti-Itch Pramoxine Lotion for Bedside Self Care Routine, Fragrance Free Hydration for Sensitive Skin 8 oz
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Why you'll love it
- Clinically tested 2-minute onset with 8 hours of relief reduces the urge to reapply throughout the day
- Steroid-free, fragrance-free, and non-comedogenic formula is a safer long-term alternative to hydrocortisone creams
- Dermatologist-developed and NEA Seal of Acceptance gives credibility for sensitive and eczema-prone users
- Dual-action itch relief plus ceramide barrier repair eliminates the need for a separate moisturizer
- FSA and HSA eligibility makes it an affordable choice for families managing recurring skin issues
Perfect for
- Relieving insect bite and mosquito bite itch within 2 minutes of application
- Soothing sunburn after beach days, pool days, or extended outdoor exposure
- Calming poison ivy, poison oak, or poison sumac irritation
- Daily moisturizing for dry, sensitive, or eczema-prone skin with built-in itch prevention
- Treating post-shave, minor skin irritation, or general itch on face, body, and hands

Developed with dermatologists*, CeraVe has a complete line of skincare to cleanse and moisturize skin. CeraVe contains the three essential ceramides (called 1, 3, and 6-II) healthy skin needs. Delivered through a controlled-release technology, this formula with ceramides helps rebuild the skin's protective barrier and locks in moisture all day.
Itch Relief Moisturizing Lotion
Product Technology
Developed with dermatologists, CeraVe Itch Relief Moisturizing Lotion temporarily relieves itching associated with minor skin irritations, insect bites and sunburn. Formulated with the anti-itch ingredient, Pramoxine Hydrochloride 1%, this product provides fast-acting, long lasting temporary itch relief. This itch relief lotion also contains three essential ceramides that helps repair and restore the skin’s barrier all in an emollient-based cream with a light-weight, velvety texture.
How to Use
Apply to affected area no more than 3 to 4 times daily.
Clinically Tested
100% of people experienced relief for even their most severe itch.*
*Clinical study of 34 subjects. Individual results may vary.
Fast Acting
2 minutes until relief for most people*
*Clinical study of 34 subjects. Individual results may vary.
Long Lasting
8 hours of relief for most people*
*Clinical study of 34 subjects. Individual results may vary.
3 Essential Ceramides
All CeraVe products contain the vital ceramides healthy skin needs to help restore and maintain its natural protective barrier.
The Role of Ceramides
Ceramides are an essential part of the skin's natural barrier. They hydrate all day to help restore the protective skin barrier.
Developed with Dermatologists*
CeraVe Itch Relief Moisturizing Cream temporarily relieves itch due to insect bites, sunburn and minor skin irritations.
NEA Seal of Acceptance*
The National Eczema Association Seal of Acceptance* only accepts products that have satisfied the criteria for use for those with eczema or sensitive skin conditions.






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The CeraVe story began in 2005 after experts noticed that many skin conditions such as acne, eczema, psoriasis and dry skin all had one thing in common: a compromised skin barrier. Developed with dermatologists, CeraVe offers a complete line of skincare & haircare products that contain three essential ceramides enhanced with a revolutionary delivery system to help restore the skin & scalp's natural protective barrier.


Product Information
[ CERAVE ANTI ITCH LOTION ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Lightweight texture that is absorbed quickly for softened skin with non-greasy feel.
[ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.
[ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skin’s natural moisture.
[ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skin’s natural barrier
[ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face; body; and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free; steroid-free; and non-comedogenic. FSA Eligible & HSA Eligible
Developed with dermatologists, CeraVe Itch Relief Moisturizing Lotion temporarily relieves itching associated with minor skin irritations, insect bites and sunburn. Formulated with the anti-itch ingredient, Pramoxine Hydrochloride 1%, this product provides fast-acting, long lasting temporary itch relief. This itch relief lotion also contains three essential ceramides that helps repair and restore the skin’s barrier all in an emollient-based cream with a light-weight, velvety texture. Steroid-free Fragrance-free Non-comedogenic Sulfate-free Gentle, non-irritating formula Accepted by the National Eczema Association Key Ingredients: 1% Pramoxine Hydrochloride: Provides fast-acting, long-lasting, temporary itch relief Ceramides: Essential for healthy skin, ceramides help restore and maintain the skin’s natural barrier
Items Details
Frequently Asked Questions
Can I use this as part of my nightly wind-down skincare ritual?
Yes, the lightweight, fragrance-free texture layers easily after a shower and pairs well with a calming pre-sleep routine, providing itch relief and ceramide hydration while you rest.
Will the scent interfere with aromatherapy or a relaxing bath?
No, the formula is completely fragrance-free, so it will not compete with essential oils, bath soaks, or scented candles you use to set a calming mood.
Does it really start working in 2 minutes so I can settle into bed without distraction?
Yes, clinical testing shows itch relief begins within about 2 minutes and continues for roughly 8 hours, which is ideal for an uninterrupted evening routine.
Can this replace my separate body moisturizer if I have eczema-prone skin?
Yes, the three essential ceramides, niacinamide, and hyaluronic acid provide daily hydration and barrier repair, so most users can use it as both their itch reliever and body moisturizer.
Is it safe to layer under my regular body oil or balm?
Yes, apply the lotion first and let it absorb for a few minutes, then follow with your preferred body oil or balm if you want extra occlusion.
I am building a self-care basket for sensitive skin; does this qualify as a wellness essential?
Yes, it covers both therapeutic and moisturizing needs, which makes it a high-value, dermatologist-developed staple for any sensitive-skin self-care gift or routine.
Can I use it on my face as part of a mindful morning routine?
Yes, it is non-comedogenic and gentle enough for facial use, so you can apply it to dry or itchy areas on the face, neck, or hands as part of your morning ritual.
Will it help with the itchy, tight feeling after a long, hot shower?
Yes, applying it within a few minutes of stepping out of the shower helps lock in moisture and relieves the post-shower itch that often comes with sensitive or eczema-prone skin.
Is this FSA or HSA eligible so I can use my wellness benefits?
Yes, this lotion is FSA and HSA eligible, making it easy to purchase with pre-tax dollars as part of your skincare and self-care budget.
Does it support a barrier-repair routine recommended by dermatologists?
Yes, it is dermatologist-developed, contains the three essential ceramides (1, 3, 6-II), and carries the National Eczema Association Seal of Acceptance.
How does this compare to a thick eczema ointment for overnight repair?
A petrolatum-based ointment is more occlusive for very severe flare-ups, but for nightly maintenance the CeraVe lotion absorbs faster, feels lighter, and still delivers ceramide repair plus itch relief in one step.
How does it compare to my usual sensitive-skin body lotion for itch?
Most standard sensitive-skin moisturizers hydrate but do not target itch, while this product adds 1% Pramoxine for fast, 8-hour relief without steroids, making it a stronger choice for reactive skin.
Is this better than taking an oral antihistamine for everyday itch?
Topical Pramoxine works at the site of irritation without the drowsiness common to oral antihistamines, so it is a gentler option for daytime or pre-bed routines when you want to stay alert.
I worry about long-term steroid exposure; is this a safer daily option?
Yes, it is completely steroid-free, so it is appropriate for ongoing daily use on sensitive, eczema-prone, or chronically itchy skin without the risks associated with long-term topical steroids.
What if my skin stings when I first apply it during a flare-up?
Mild, brief tingling can occur on broken or very irritated skin, but it usually settles within a minute; if burning persists or worsens, rinse and consult a dermatologist.
Will the niacinamide interact with my other active skincare products?
Niacinamide is well tolerated alongside most actives, but if you use strong exfoliants like high-strength retinol or acids, alternate them on different nights to avoid over-stimulation.
How do I apply CeraVe Anti-Itch Moisturizing Lotion for the best results?
Apply a thin layer to clean, affected skin on the face, body, or hands as needed, and reapply up to three or four times daily, or as directed by a dermatologist, especially after bathing or sun exposure.
How long does one 8 oz bottle typically last with daily use?
With once- or twice-daily whole-body application, an 8 oz bottle generally lasts about four to six weeks for a single user and longer when shared across a family or used only on trouble spots.
Can I use this lotion on my face, body, and hands all in one routine?
Yes, the lightweight, non-greasy formula is designed for use on the face, body, and hands, so you can simplify your routine by replacing multiple moisturizers with this single product.
Is this product compatible with my regular sunscreen and makeup?
Yes, apply the lotion first, allow it to absorb for a few minutes, and then layer sunscreen, makeup, or other skincare on top without pilling or interference.
Can I use it together with my prescription eczema or acne treatment?
In most cases, yes, but apply your prescription product first, give it a few minutes to absorb, and then apply this lotion on top; always follow the specific instructions from your prescribing dermatologist.
What comes in the box when I order, and do I need to buy anything else to start using it?
The package includes one 8 oz bottle of CeraVe Anti-Itch Moisturizing Lotion ready to use, and you do not need any additional accessories, though a small travel decanter can be helpful for air travel.
Is this product safe and stable to use past its printed expiration date?
For best performance, texture, and preservative effectiveness, use the lotion before the expiration date on the bottle or packaging, and discard if the smell, color, or consistency changes.
Can I use it on pets or animals if they have itchy skin?
This product is formulated and tested for human use only, so do not apply it to pets; consult a veterinarian for any animal skin concerns.
What is the difference between an anti-itch lotion and a regular moisturizer?
A regular moisturizer focuses on hydration, while an anti-itch lotion adds an active ingredient like 1% Pramoxine Hydrochloride to interrupt the itch signal, providing both relief and barrier repair in one step.

